Genome Sequence of Neisseria meningitidis Serogroup B Strain H44/76
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چکیده
منابع مشابه
Complete genome sequence of Neisseria meningitidis serogroup B strain MC58.
The 2,272,351-base pair genome of Neisseria meningitidis strain MC58 (serogroup B), a causative agent of meningitis and septicemia, contains 2158 predicted coding regions, 1158 (53.7%) of which were assigned a biological role. Three major islands of horizontal DNA transfer were identified; two of these contain genes encoding proteins involved in pathogenicity, and the third island contains codi...
متن کاملGenome sequence of Neisseria meningitidis serogroup B strain H44/76.
Neisseria meningitidis is an obligate human pathogen. While it is a frequent commensal of the upper respiratory tract, in some individuals the bacterium spreads to the bloodstream, causing meningitis and/or sepsis, which are serious conditions with high morbidity and mortality. Here we report the availability of the genome sequence of the widely used serogroup B laboratory strain H44/76.
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Koel Bhattacharya, Suman Kanungo, Dipika Sur, Banwari Lal Sarkar, Byomkesh Manna, Anna Lena Lopez,1 Manjira Bhattacharya, Suman Nandy, and Swapan Kumar Niyogi Author affi liations: National institute of Cholera and Enteric Diseases, Kolkata, India (K. Bhattacharya, S. Kanungo, D. Sur, B.L. Sarkar, B. Manna, M. Bhattacharya, S. Nandy, S.K. Niyogi); and International Vaccine Institute, Seoul, Sou...
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Serogroup A meningococci are a leading cause of bacterial meningitis in children and young adults worldwide. However, the genetic basis of serogroup A strains' virulence and their epidemiological properties remain poorly understood. Therefore, we sequenced the complete genome of the transformable Neisseria meningitidis serogroup A strain WUE2594.
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Background: Artificial oligonucleotides like DNA or RNA aptamers can be used as biodiagnostic alternatives for antibodies to detect pathogens. Comparing to antibodies, artificial oligonucleotides are produced easily at lower costs and are more stable. Neisseria meningitidis, the causative agent of meningitis, is responsible for about 1% of infections in an epidemic period. Specific DNA aptamers...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2011
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.01331-10